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BOOK SUMMARY :

Polyunsaturated fatty acid metabolism explores a number of major roles of pufa in the body including its role as a component of cell membranes and how it provides substrates for the synthesis of lipid second messengers recent studies are unraveling the effect of interactions between diet and endocrine factors and genetic and epigenetic variation on the regulation of pufa biosynthesis in animalspolyunsaturated fatty acid metabolism explores a number of major roles of pufa in the body including its role as a component of cell membranes and how it provides substrates for the synthesis of lipid second messengers recent studies are unraveling the effect of interactions between diet and endocrine factors and genetic and epigenetic polyunsaturated fatty acids pufa play important roles in the normal physiology and in pathological states including inflammation and cancer while much is known about the biosynthesis and biological activities of eicosanoids derived from 6 pufa our understanding of the corresponding 3 series ethyl oleate short chain short chain fatty acids are the primary end products of bacterial metabolism in the human large intestine moreover while short chain fatty acids are formed from various precursors by anaerobic micro organisms carbohydrates are the most common progenitors of short chain fatty acidsmajor depressive disorder mdd in children and adolescents is a major public health problem with an estimated point prevalence of between 23 in school age children 612 years and 39

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